AMH levels measured with the revised protocol were collated to generate an age-specific reference range, with median levels peaking at 27 years then declining with advancing age. ![]() In all samples with detectable AMH levels, the revised protocol yielded a higher concentration compared with the original protocol, the magnitude shift ranging from 3.4 to 283.3 % (median 68.0 %). The original protocol significantly underestimated AMH levels compared with the revised protocol ( p < 0.001), the median being 8.4 and 14.2 pmol/L, respectively. Serum AMH levels were measured for 492 natural conception first trimester pregnant women using the original and revised Gen II assay. The aim of this study was to compare AMH levels measured with the original and revised Gen II assay and to establish a fertile female reference range for the revised protocol. However, in July 2013, the protocol was revised due to falsely low readings. Since 2011, the standard test for AMH has been the Beckman Coulter Generation (Gen) II assay. ![]() Anti-Müllerian hormone (AMH) is used as a marker for ovarian reserve.
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